Antabuse is also known by the name disulfiram. A very unpleasant reaction occurs when a patient under disulfiram treatment ingests alcohol. Disulfiram plus even small amounts of alcohol produces flushing, throbbing in the head and neck, respiratory difficulty, nausea, vomiting, sweating, thirst, chest pain, blurred vision, and confusion. In severe reactions, there may be acute congestive heart failure, unconsciousness, convulsions, and death. The intensity of the reaction is generally proportional to the amount of disulfiram and alcohol ingested.
Disulfiram should never be administered to a patient without his/her full knowledge or when he/she is intoxicated.
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